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Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-c]Quinoline Derivatives as Potential Antileukemia Agents

Herein, we design and synthesize an array of benzofuro[3,2-c]quinolines starting from 3-(2-methoxyphenyl)quinolin-4(1H)ones via a sequential chlorination/demethylation, intramolecular cyclization pathway. This sequential transformation was efficient, conducted under metal-free and mild reaction cond...

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Detalles Bibliográficos
Autores principales: Lin, Ying, Xing, Dong, Wu, Wen-Biao, Xu, Gao-Ya, Yu, Li-Fang, Tang, Jie, Zhou, Yu-Bo, Li, Jia, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983037/
https://www.ncbi.nlm.nih.gov/pubmed/31947824
http://dx.doi.org/10.3390/molecules25010203