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Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates

Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a variety of applications: bambuterol and physostig...

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Detalles Bibliográficos
Autores principales: Bosak, Anita, Bavec, Aljoša, Konte, Tilen, Šinko, Goran, Kovarik, Zrinka, Goličnik, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983073/
https://www.ncbi.nlm.nih.gov/pubmed/31947900
http://dx.doi.org/10.3390/molecules25010211