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On the Reversible and Irreversible Inhibition of Rhodesain by Curcumin
Previously, it was suggested that the natural compound curcumin is an irreversible inhibitor of rhodesain, the major lysosomal cysteine protease of the protozoan parasite Trypanosoma brucei. The suggestion was based on a time-dependent inhibition of the enzyme by curcumin and a lack of recovery of a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983121/ https://www.ncbi.nlm.nih.gov/pubmed/31905815 http://dx.doi.org/10.3390/molecules25010143 |