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A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions

The alkylation of a series of nitroindazole derivatives with 1,2-dibromoethane afforded the corresponding N-(2-bromoethyl)- and N-vinyl-nitro-1H-indazoles. The Cu(I)-catalysed azide- alkyne 1,3-dipolar cycloaddition was selected to substitute the nitroindazole core with 1,4-disubstituted triazole un...

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Detalles Bibliográficos
Autores principales: Eddahmi, Mohammed, Moura, Nuno M. M., Bouissane, Latifa, Amiri, Ouafa, Faustino, M. Amparo F., Cavaleiro, José A. S., Mendes, Ricardo F., Paz, Filipe A. A., Neves, Maria G. P. M. S., Rakib, El Mostapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983193/
https://www.ncbi.nlm.nih.gov/pubmed/31905680
http://dx.doi.org/10.3390/molecules25010126