Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly

The fact that the number of people with Alzheimer’s disease is increasing, combined with the limited availability of drugs for its treatment, emphasize the need for the development of novel effective therapeutics for treating this brain disorder. Herein, we focus on generating 12 chalcone-donepezil...

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Detalles Bibliográficos
Autores principales: Thamban Chandrika, Nishad, Fosso, Marina Y., Tsodikov, Oleg V., LeVine, Harry, Garneau-Tsodikova, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983213/
https://www.ncbi.nlm.nih.gov/pubmed/31878304
http://dx.doi.org/10.3390/molecules25010077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983213/
https://www.ncbi.nlm.nih.gov/pubmed/31878304
http://dx.doi.org/10.3390/molecules25010077

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