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A de novo peroxidase is also a promiscuous yet stereoselective carbene transferase

By constructing an in vivo-assembled, catalytically proficient peroxidase, C45, we have recently demonstrated the catalytic potential of simple, de novo-designed heme proteins. Here, we show that C45’s enzymatic activity extends to the efficient and stereoselective intermolecular transfer of carbene...

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Detalles Bibliográficos
Autores principales: Stenner, Richard, Steventon, Jack W., Seddon, Annela, Anderson, J. L. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983366/
https://www.ncbi.nlm.nih.gov/pubmed/31896585
http://dx.doi.org/10.1073/pnas.1915054117