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Localization and Accumulation Studies of Dacomitinib in Rat Intestines and Skin by Immunohistochemistry

Dacomitinib, a second-generation tyrosine kinase inhibitor, was irreversible inhibitor forming covalent bonds with the kinase domains of EGFR and other ErbB family receptors. Dacomitinib has been approved for the treatment of locally advanced or metastatic non-small cell lung cancer. In this study,...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yutaro, Saita, Tetsuya, Oka, Asuki, Kataoka, Hiroto, Shin, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983371/
https://www.ncbi.nlm.nih.gov/pubmed/32001948
http://dx.doi.org/10.1267/ahc.19031