Cargando…
Host protein glycosylation in nucleic acid vaccines as a potential hurdle in vaccine design for nonviral pathogens
Nucleic acid vaccines introduce the genetic materials encoding antigenic proteins into host cells. If these proteins are directed into the secretory pathway with a signal/leader sequence, they will be exposed to the host’s glycosylation machinery, and, if their amino acid sequences contain consensus...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983373/ https://www.ncbi.nlm.nih.gov/pubmed/31907319 http://dx.doi.org/10.1073/pnas.1916131117 |