Quantitative microscopy reveals dynamics and fate of clustered IRE1α

The endoplasmic reticulum (ER) membrane-resident stress sensor inositol-requiring enzyme 1 (IRE1) governs the most evolutionarily conserved branch of the unfolded protein response. Upon sensing an accumulation of unfolded proteins in the ER lumen, IRE1 activates its cytoplasmic kinase and ribonuclea...

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Detalles Bibliográficos
Autores principales: Belyy, Vladislav, Tran, Ngoc-Han, Walter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983381/
https://www.ncbi.nlm.nih.gov/pubmed/31871156
http://dx.doi.org/10.1073/pnas.1915311117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983381/
https://www.ncbi.nlm.nih.gov/pubmed/31871156
http://dx.doi.org/10.1073/pnas.1915311117

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