Three-dimensional nucleus-to-cytoplasm ratios provide better discrimination of normal and lung adenocarcinoma cells than in two dimensions

We acquired multiphoton images of normal and lung adenocarcinoma cell lines in three dimensions. Image stacks of the cells were then processed to obtain nucleus-to-cytoplasm (N/C) ratios in two and three dimensions. While N/C ratios in three dimensions can be unambiguously determined from the volume...

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Detalles Bibliográficos
Autores principales: Huang, Hsu-Cheng, Chiang, Shu-Jen, Wen, Shu-Han, Lee, Pei-Jung, Chen, Huei-Wen, Chen, Yang-Fang, Dong, Chen-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2019
Materias:
JBO Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983472/
https://www.ncbi.nlm.nih.gov/pubmed/31432656
http://dx.doi.org/10.1117/1.JBO.24.8.080502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983472/
https://www.ncbi.nlm.nih.gov/pubmed/31432656
http://dx.doi.org/10.1117/1.JBO.24.8.080502

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