Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen

AIMS: Lidocaine is used to treat neonatal seizures refractory to other anticonvulsants. It is effective, but also associated with cardiac toxicity. Previous studies have reported on the pharmacokinetics of lidocaine in preterm and term neonates and proposed a dosing regimen for effective and safe li...

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Detalles Bibliográficos
Autores principales: Favié, Laurent M.A., Huitema, Alwin D.R., van den Broek, Marcel P.H., Rademaker, Carin M.A., de Haan, Timo R., van Straaten, Henrica L.M., Simons, Sinno H.P., Rijken, Monique, Nuytemans, Debbie H.G.M., Egberts, Toine C.G., Groenendaal, Floris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983510/
https://www.ncbi.nlm.nih.gov/pubmed/31663153
http://dx.doi.org/10.1111/bcp.14136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983510/
https://www.ncbi.nlm.nih.gov/pubmed/31663153
http://dx.doi.org/10.1111/bcp.14136

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