Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra

Hydra possesses three distinct stem cell populations that continuously self-renew and prevent aging in Hydra vulgaris. However, sexual animals from the H. oligactis cold-sensitive strain Ho_CS develop an aging phenotype upon gametogenesis induction, initiated by the loss of interstitial stem cells....

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Detalles Bibliográficos
Autores principales: Tomczyk, Szymon, Suknovic, Nenad, Schenkelaars, Quentin, Wenger, Yvan, Ekundayo, Kazadi, Buzgariu, Wanda, Bauer, Christoph, Fischer, Kathleen, Austad, Steven, Galliot, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983715/
https://www.ncbi.nlm.nih.gov/pubmed/31862842
http://dx.doi.org/10.1242/dev.177840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983715/
https://www.ncbi.nlm.nih.gov/pubmed/31862842
http://dx.doi.org/10.1242/dev.177840

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