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A platform for target prediction of phenotypic screening hit molecules

Many drug discovery programmes, particularly for infectious diseases, are conducted phenotypically. Identifying the targets of phenotypic screening hits experimentally can be complex, time-consuming, and expensive. However, it would be valuable to know what the molecular target(s) is, as knowledge o...

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Detalles Bibliográficos
Autores principales: Homeyer, Nadine, van Deursen, Ruud, Ochoa-Montaño, Bernardo, Heikamp, Kathrin, Ray, Peter, Zuccotto, Fabio, Blundell, Tom L., Gilbert, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science, Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983931/
https://www.ncbi.nlm.nih.gov/pubmed/31836397
http://dx.doi.org/10.1016/j.jmgm.2019.107485