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A platform for target prediction of phenotypic screening hit molecules
Many drug discovery programmes, particularly for infectious diseases, are conducted phenotypically. Identifying the targets of phenotypic screening hits experimentally can be complex, time-consuming, and expensive. However, it would be valuable to know what the molecular target(s) is, as knowledge o...
Autores principales: | Homeyer, Nadine, van Deursen, Ruud, Ochoa-Montaño, Bernardo, Heikamp, Kathrin, Ray, Peter, Zuccotto, Fabio, Blundell, Tom L., Gilbert, Ian H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science, Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983931/ https://www.ncbi.nlm.nih.gov/pubmed/31836397 http://dx.doi.org/10.1016/j.jmgm.2019.107485 |
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