Influence of cytochrome P450 3A5 (CYP3A5) genetic polymorphism on dose-adjusted plasma levels of carbamazepine in epileptic patients in South Indian population

AIM: The aim of the study was to compare the dose-adjusted plasma levels of carbamazepine (CBZ) among expressers and nonexpressers of cytochrome P450 3A5 (CYP3A5)* 3 genotypes. SUBJECTS AND METHODS: The study was carried out in 100 epileptic patients who were on CBZ monotherapy. Steady-state plasma...

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Detalles Bibliográficos
Autores principales: Ganesapandian, Mahalakshmi, Ramasamy, Kesavan, Adithan, Surendiran, Narayan, Sunil K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984020/
https://www.ncbi.nlm.nih.gov/pubmed/32029960
http://dx.doi.org/10.4103/ijp.IJP_122_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984020/
https://www.ncbi.nlm.nih.gov/pubmed/32029960
http://dx.doi.org/10.4103/ijp.IJP_122_19

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