Decrease of Cardiac Parkin Protein in Obese Mice

Mitophagy plays a major role in heart physiology. Impairment of Parkin-dependent mitophagy in heart is known to be deleterious. Obesity is a known cardiovascular risk factor. Impaired autophagy has been reported in models of obesity or hyperlipidemia/hypercholesterolemia; however less is known regar...

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Detalles Bibliográficos
Autores principales: Thomas, Amandine, Marek-Iannucci, Stefanie, Tucker, Kyle C., Andres, Allen M., Gottlieb, Roberta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984192/
https://www.ncbi.nlm.nih.gov/pubmed/32039238
http://dx.doi.org/10.3389/fcvm.2019.00191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984192/
https://www.ncbi.nlm.nih.gov/pubmed/32039238
http://dx.doi.org/10.3389/fcvm.2019.00191

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