The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability

Recent studies indicate a causative relationship between defects in autophagy and dopaminergic neuron degeneration in Parkinson disease (PD). However, it is not fully understood how autophagy is regulated in the context of PD. Here we identify USP24 (ubiquitin specific peptidase 24), a gene located...

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Detalles Bibliográficos
Autores principales: Thayer, Julia A., Awad, Ola, Hegdekar, Nivedita, Sarkar, Chinmoy, Tesfay, Henok, Burt, Cameran, Zeng, Xianmin, Feldman, Ricardo A., Lipinski, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984603/
https://www.ncbi.nlm.nih.gov/pubmed/30957634
http://dx.doi.org/10.1080/15548627.2019.1598754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984603/
https://www.ncbi.nlm.nih.gov/pubmed/30957634
http://dx.doi.org/10.1080/15548627.2019.1598754

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