MicroRNA-15a-5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP-2 signaling pathway

The aim of the present study was to investigate the role of microRNA-15a-5p (miR-15a-5p) in pulmonary arterial hypertension (PAH) and elucidate the underlying pro-apoptotic mechanism. Reverse transcription-quantitative PCR analysis and gene microarray hybridization were used to measure the expressio...

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Detalles Bibliográficos
Autores principales: Zhang, Wenmei, Li, Yanna, Xi, Xin, Zhu, Guangfa, Wang, Shenghao, Liu, Yan, Song, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984778/
https://www.ncbi.nlm.nih.gov/pubmed/31894295
http://dx.doi.org/10.3892/ijmm.2019.4434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984778/
https://www.ncbi.nlm.nih.gov/pubmed/31894295
http://dx.doi.org/10.3892/ijmm.2019.4434

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