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MicroRNA-15a-5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP-2 signaling pathway
The aim of the present study was to investigate the role of microRNA-15a-5p (miR-15a-5p) in pulmonary arterial hypertension (PAH) and elucidate the underlying pro-apoptotic mechanism. Reverse transcription-quantitative PCR analysis and gene microarray hybridization were used to measure the expressio...
Autores principales: | Zhang, Wenmei, Li, Yanna, Xi, Xin, Zhu, Guangfa, Wang, Shenghao, Liu, Yan, Song, Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984778/ https://www.ncbi.nlm.nih.gov/pubmed/31894295 http://dx.doi.org/10.3892/ijmm.2019.4434 |
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