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CCR4-NOT transcription complex subunit 2 regulates TRAIL sensitivity in non-small-cell lung cancer cells via the STAT3 pathway

TRAIL is an attractive candidate for anticancer therapy in a variety of tumors since it targets only tumors and not normal tissue. However, a remaining major hurdle is that the majority of tumors exhibit a resistance mechanism against the effects of TRAIL via the induction of anti-apoptotic signalin...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Ok, Kang, Shi-Eun, Choi, Minji, Rhee, Ki-Jong, Yun, Miyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984779/
https://www.ncbi.nlm.nih.gov/pubmed/31894259
http://dx.doi.org/10.3892/ijmm.2019.4425