Cargando…
CCR4-NOT transcription complex subunit 2 regulates TRAIL sensitivity in non-small-cell lung cancer cells via the STAT3 pathway
TRAIL is an attractive candidate for anticancer therapy in a variety of tumors since it targets only tumors and not normal tissue. However, a remaining major hurdle is that the majority of tumors exhibit a resistance mechanism against the effects of TRAIL via the induction of anti-apoptotic signalin...
Autores principales: | Kim, Eun-Ok, Kang, Shi-Eun, Choi, Minji, Rhee, Ki-Jong, Yun, Miyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984779/ https://www.ncbi.nlm.nih.gov/pubmed/31894259 http://dx.doi.org/10.3892/ijmm.2019.4425 |
Ejemplares similares
-
The Not5 Subunit of the Ccr4-Not Complex Connects Transcription and Translation
por: Villanyi, Zoltan, et al.
Publicado: (2014) -
Herbal Medicines Showing Synergistic Effects with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) against A549 TRAIL-resistant Lung Cancer Cells: A Screening Study
por: Chiang, Shuen Cheng, et al.
Publicado: (2018) -
Method to Determine the Optimal Aptamer-to-Bead Ratio by Using Flow Cytometry
por: Lee, Sun Young, et al.
Publicado: (2023) -
Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
por: Trivedi, Rachana, et al.
Publicado: (2015) -
The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence
por: Mittal, Saloni, et al.
Publicado: (2011)