Clinically relevant GSK-3β inhibitor 9-ING-41 is active as a single agent and in combination with other antitumor therapies in human renal cancer

Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase, is involved in a broad range of pathological processes including cancer. GSK-3 has two isoforms, GSK-3α and GSK-3β, and GSK-3β has been recognized as a therapeutic target for the development of new anticancer drugs. The present study aim...

Descripción completa

Detalles Bibliográficos
Autores principales: Anraku, Tsutomu, Kuroki, Hiroo, Kazama, Akira, Bilim, Vladimir, Tasaki, Masaaki, Schmitt, Daniel, Mazar, Andrew, Giles, Francis J., Ugolkov, Andrey, Tomita, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984786/
https://www.ncbi.nlm.nih.gov/pubmed/31894292
http://dx.doi.org/10.3892/ijmm.2019.4427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984786/
https://www.ncbi.nlm.nih.gov/pubmed/31894292
http://dx.doi.org/10.3892/ijmm.2019.4427

Ejemplares similares