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Clinically relevant GSK-3β inhibitor 9-ING-41 is active as a single agent and in combination with other antitumor therapies in human renal cancer

Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase, is involved in a broad range of pathological processes including cancer. GSK-3 has two isoforms, GSK-3α and GSK-3β, and GSK-3β has been recognized as a therapeutic target for the development of new anticancer drugs. The present study aim...

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Detalles Bibliográficos
Autores principales:	Anraku, Tsutomu, Kuroki, Hiroo, Kazama, Akira, Bilim, Vladimir, Tasaki, Masaaki, Schmitt, Daniel, Mazar, Andrew, Giles, Francis J., Ugolkov, Andrey, Tomita, Yoshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984786/ https://www.ncbi.nlm.nih.gov/pubmed/31894292 http://dx.doi.org/10.3892/ijmm.2019.4427

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