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Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar

BACKGROUND: Higher-order structure (HOS) assessment is an important component of biosimilarity evaluations. While established spectroscopic methods are routinely used to characterize structure and evaluate similarity, the addition of X-ray crystallographic analysis to these biophysical methods enabl...

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Detalles Bibliográficos
Autores principales: Lerch, Thomas F., Sharpe, Penelope, Mayclin, Stephen J., Edwards, Thomas E., Polleck, Sharon, Rouse, Jason C., Zou, Qin, Conlon, Hugh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985046/
https://www.ncbi.nlm.nih.gov/pubmed/31650490
http://dx.doi.org/10.1007/s40259-019-00390-1