Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

The rate and extent of drug dissolution in the gastrointestinal (GI) tract are highly dependent upon drug physicochemical properties and GI fluid properties. Biorelevant dissolution media (BDM), which aim to facilitate in vitro prediction of in vivo dissolution performance, have evolved with our und...

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Detalles Bibliográficos
Autores principales: Mudie, Deanna M., Samiei, Nasim, Marshall, Derrick J., Amidon, Gregory E., Bergström, Christel A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985051/
https://www.ncbi.nlm.nih.gov/pubmed/31989343
http://dx.doi.org/10.1208/s12248-020-0417-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985051/
https://www.ncbi.nlm.nih.gov/pubmed/31989343
http://dx.doi.org/10.1208/s12248-020-0417-8

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