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Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
The rate and extent of drug dissolution in the gastrointestinal (GI) tract are highly dependent upon drug physicochemical properties and GI fluid properties. Biorelevant dissolution media (BDM), which aim to facilitate in vitro prediction of in vivo dissolution performance, have evolved with our und...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985051/ https://www.ncbi.nlm.nih.gov/pubmed/31989343 http://dx.doi.org/10.1208/s12248-020-0417-8 |