Simultaneous Knockdown of Sprouty2 and PTEN Promotes Axon Elongation of Adult Sensory Neurons

Sprouty2 (Spry2) and phosphatase and tensin homolog deleted on chromosome 10 (PTEN) are both well-established regulators of receptor tyrosine kinase (RTK) signaling, and knockdown of Spry2 or PTEN enhances axon regeneration of dorsal root ganglia (DRG) neurons. The major role of Spry2 is the inhibit...

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Detalles Bibliográficos
Autores principales: Jamsuwan, Sataporn, Klimaschewski, Lars, Hausott, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985068/
https://www.ncbi.nlm.nih.gov/pubmed/32038175
http://dx.doi.org/10.3389/fncel.2019.00583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985068/
https://www.ncbi.nlm.nih.gov/pubmed/32038175
http://dx.doi.org/10.3389/fncel.2019.00583

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