Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib

PURPOSE: Fusion genes can be therapeutically relevant if they result in constitutive activation of oncogenes or repression of tumor suppressors. However, the prevalence and role of fusion genes in female cancers remain largely unexplored. Here, we investigate the fusion gene landscape in triple-nega...

Descripción completa

Detalles Bibliográficos
Autores principales: Eismann, Julia, Heng, Yujing J., Waldschmidt, Johannes M., Vlachos, Ioannis S., Gray, Kathryn P., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A., Murphy, Charles J., Nabavi, Sheida, Wulf, Gerburg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article – Clinical Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985087/
https://www.ncbi.nlm.nih.gov/pubmed/31745703
http://dx.doi.org/10.1007/s00432-019-03078-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985087/
https://www.ncbi.nlm.nih.gov/pubmed/31745703
http://dx.doi.org/10.1007/s00432-019-03078-9

Ejemplares similares