A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy

Selenocompounds (SeCs) are promising therapeutic agents for a wide range of diseases including cancer. The treatment results are heterogeneous and dependent on both the chemical species and the concentration of SeCs. Moreover, the mechanisms of action are poorly revealed, which most probably is due...

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Detalles Bibliográficos
Autores principales: Zheng, Wenyi, He, Rui, Boada, Roberto, Subirana, Maria Angels, Ginman, Tobias, Ottosson, Håkan, Valiente, Manuel, Zhao, Ying, Hassan, Moustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985102/
https://www.ncbi.nlm.nih.gov/pubmed/31988319
http://dx.doi.org/10.1038/s41598-020-57983-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985102/
https://www.ncbi.nlm.nih.gov/pubmed/31988319
http://dx.doi.org/10.1038/s41598-020-57983-y

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