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Annexin A8 regulates Wnt signaling to maintain the phenotypic plasticity of retinal pigment epithelial cells

Wnt signalling mediates complex cell-cellinteractions during development and proliferation. Annexin A8 (AnxA8), a calcium-dependent phospholipid-binding protein, and canonical Wnt signalling mechanisms have both been implicated in retinal pigment epithelial (RPE) cell differentiation. The aim here w...

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Detalles Bibliográficos
Autores principales: Lueck, Katharina, Carr, Amanda-Jayne F., Yu, Lu, Greenwood, John, Moss, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985107/
https://www.ncbi.nlm.nih.gov/pubmed/31988387
http://dx.doi.org/10.1038/s41598-020-58296-w