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Lymphatic endothelial cells prime naïve CD8(+) T cells into memory cells under steady-state conditions
Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8(+) T cells to drive their proliferation despite lacking key costimulatory molecules. However, the functional consequence of LEC priming of CD8(+) T...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985113/ https://www.ncbi.nlm.nih.gov/pubmed/31988323 http://dx.doi.org/10.1038/s41467-019-14127-9 |