Lymphatic endothelial cells prime naïve CD8(+) T cells into memory cells under steady-state conditions

Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8(+) T cells to drive their proliferation despite lacking key costimulatory molecules. However, the functional consequence of LEC priming of CD8(+) T...

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Detalles Bibliográficos
Autores principales: Vokali, Efthymia, Yu, Shann S., Hirosue, Sachiko, Rinçon-Restrepo, Marcela, V. Duraes, Fernanda, Scherer, Stefanie, Corthésy-Henrioud, Patricia, Kilarski, Witold W., Mondino, Anna, Zehn, Dietmar, Hugues, Stéphanie, Swartz, Melody A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985113/
https://www.ncbi.nlm.nih.gov/pubmed/31988323
http://dx.doi.org/10.1038/s41467-019-14127-9

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