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Primary cilia control cell alignment and patterning in bone development via ceramide-PKCζ-β-catenin signaling
Intraflagellar transport (IFT) proteins are essential for cilia assembly and function. IFT protein mutations lead to ciliopathies, which manifest as variable skeletal abnormalities. However, how IFT proteins regulate cell alignment during bone development is unknown. Here, we show that the deletion...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985158/ https://www.ncbi.nlm.nih.gov/pubmed/31988398 http://dx.doi.org/10.1038/s42003-020-0767-x |