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The concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity
Previous studies have shown that tumor necrosis factor (TNF)-α is a mediator of hepatotoxicity in liver injury. Moreover, TNF-α has also been reported to have a protective effect in liver regeneration, yet the function of TNF-α during liver injury remains controversial. Here, we report that the conc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985193/ https://www.ncbi.nlm.nih.gov/pubmed/31988281 http://dx.doi.org/10.1038/s41419-020-2264-z |