The concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity

Previous studies have shown that tumor necrosis factor (TNF)-α is a mediator of hepatotoxicity in liver injury. Moreover, TNF-α has also been reported to have a protective effect in liver regeneration, yet the function of TNF-α during liver injury remains controversial. Here, we report that the conc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Shanmin, Jiang, Jinghua, Jing, Yingying, Liu, Wenting, Yang, Xue, Hou, Xiaojuan, Gao, Lu, Wei, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985193/
https://www.ncbi.nlm.nih.gov/pubmed/31988281
http://dx.doi.org/10.1038/s41419-020-2264-z

Ejemplares similares

Ejemplares similares