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Molecular Mechanisms and Therapeutics for SBMA/Kennedy’s Disease

Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disease caused by a polyglutamine (polyQ) expansion in the androgen receptor (AR). Despite the fact that the monogenic cause of SBMA has been known for nearly 3 decades, there is no effective treatment for this disease, underscoring the co...

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Detalles Bibliográficos
Autores principales: Arnold, Frederick J., Merry, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985201/
https://www.ncbi.nlm.nih.gov/pubmed/31686397
http://dx.doi.org/10.1007/s13311-019-00790-9