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Single-cell dispensing and ‘real-time’ cell classification using convolutional neural networks for higher efficiency in single-cell cloning

Single-cell dispensing for automated cell isolation of individual cells has gained increased attention in the biopharmaceutical industry, mainly for production of clonal cell lines. Here, machine learning for classification of cell images is applied for ‘real-time’ cell viability sorting on a single...

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Detalles Bibliográficos
Autores principales: Riba, Julian, Schoendube, Jonas, Zimmermann, Stefan, Koltay, Peter, Zengerle, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985245/
https://www.ncbi.nlm.nih.gov/pubmed/31988355
http://dx.doi.org/10.1038/s41598-020-57900-3