Constitutive CD8 expression drives innate CD8(+) T-cell differentiation via induction of iNKT2 cells

Temporal down-regulation of the CD8 co-receptor after receiving positive-selection signals has been proposed to serve as an important determinant to segregate helper versus cytotoxic lineages by generating differences in the duration of TCR signaling between MHC-I and MHC-II selected thymocytes. By...

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Detalles Bibliográficos
Autores principales: Kojo, Satoshi, Ohno-Oishi, Michiko, Wada, Hisashi, Nieke, Sebastian, Seo, Wooseok, Muroi, Sawako, Taniuchi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985454/
https://www.ncbi.nlm.nih.gov/pubmed/31980555
http://dx.doi.org/10.26508/lsa.202000642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985454/
https://www.ncbi.nlm.nih.gov/pubmed/31980555
http://dx.doi.org/10.26508/lsa.202000642

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