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Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions
Mast cells are inflammatory immune cells that play an essential role in mediating allergic reactions in humans. It is well-known that mast cell activation is critically regulated by intracellular calcium ion (Ca(2+)) concentrations. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a G-protein...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985555/ https://www.ncbi.nlm.nih.gov/pubmed/32038646 http://dx.doi.org/10.3389/fimmu.2019.03143 |