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Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions

Mast cells are inflammatory immune cells that play an essential role in mediating allergic reactions in humans. It is well-known that mast cell activation is critically regulated by intracellular calcium ion (Ca(2+)) concentrations. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a G-protein...

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Detalles Bibliográficos
Autores principales:	Occhiuto, Christopher J., Kammala, Ananth K., Yang, Canchai, Nellutla, Rithvik, Garcia, Marco, Gomez, Gregorio, Subramanian, Hariharan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985555/ https://www.ncbi.nlm.nih.gov/pubmed/32038646 http://dx.doi.org/10.3389/fimmu.2019.03143

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