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Using SNP Weights Derived From Gene Expression Modules to Improve GWAS Power for Feed Efficiency in Pigs

The “large p small n” problem has posed a significant challenge in the analysis and interpretation of genome-wide association studies (GWAS). The use of prior information to rank genomic regions and perform SNP selection could increase the power of GWAS. In this study, we propose the use of gene exp...

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Detalles Bibliográficos
Autores principales: Keel, Brittney N., Snelling, Warren M., Lindholm-Perry, Amanda K., Oliver, William T., Kuehn, Larry A., Rohrer, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985563/
https://www.ncbi.nlm.nih.gov/pubmed/32038708
http://dx.doi.org/10.3389/fgene.2019.01339