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TIM‐4 interference in Kupffer cells against CCL4‐induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway

OBJECTIVES: T‐cell immunoglobulin domain and mucin domain‐4 (TIM‐4) is selectively expressed on antigen‐presenting cells (APCs) and modulates various immune responses. However, the role of TIM‐4 expressed by Kupffer cells (KCs) in liver fibrosis remains unclear. The present study aimed to explore wh...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Chen, Guoyong, Wang, Jingyuan, Deng, Minghua, Yuan, Fangchao, Gong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985653/
https://www.ncbi.nlm.nih.gov/pubmed/31755616
http://dx.doi.org/10.1111/cpr.12731