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SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection

OBJECTIVES: Secondary bacterial pneumonia is common following influenza infection. However, it remains unclear about the underlying molecular mechanisms. MATERIALS AND METHODS: We established a mouse model of post‐influenza S aureus pneumonia using conditional Shp2 knockout mice (LysM(Cre/+):Shp2(fl...

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Detalles Bibliográficos
Autores principales: Ouyang, Wei, Liu, Chao, Pan, Ying, Han, Yu, Yang, Liping, Xia, Jingyan, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985656/
https://www.ncbi.nlm.nih.gov/pubmed/31782850
http://dx.doi.org/10.1111/cpr.12721