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Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction

OBJECTIVES: We investigated the anti‐cancer activity of pentamidine, an anti‐protozoal cationic aromatic diamidine drug, in prostate cancer cells and aimed to provide valuable insights for improving the efficacy of prostate cancer treatment. MATERIALS AND METHODS: Prostate cancer cell lines and epit...

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Detalles Bibliográficos
Autores principales: Liu, Lin, Wang, Fan, Tong, Yu, Li, Lin‐Feng, Liu, Yanfeng, Gao, Wei‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985668/
https://www.ncbi.nlm.nih.gov/pubmed/31721355
http://dx.doi.org/10.1111/cpr.12718