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Inhibition of lysine‐specific demethylase 1A suppresses neointimal hyperplasia by targeting bone morphogenetic protein 2 and mediating vascular smooth muscle cell phenotype

OBJECTIVES: Vascular disorders are associated with phenotypical switching of vascular smooth muscle cells (VSMCs). We investigated the effect of bone morphogenetic protein (BMP)‐2 in controlling VSMC phenotype and vascular disorder progression. Lysine (K)‐specific demethylase 1A (KDM1A) has been ide...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaobo, Huang, Tao, Zhai, Heng, Peng, Wenpeng, Zhou, Yong, Li, Qi, Yang, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985674/
https://www.ncbi.nlm.nih.gov/pubmed/31737960
http://dx.doi.org/10.1111/cpr.12711