Cargando…

Biochemical Activity of Vaborbactam

The most common mechanism of resistance to β-lactams antibiotics in Gram-negative bacteria is production of β-lactamase enzymes capable of cleaving the β-lactam ring. Inhibition of β-lactamase activity with small-molecule drugs is a proven strategy to restore the potency of many β-lactam antibiotics...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsivkovski, Ruslan, Lomovskaya, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985712/
https://www.ncbi.nlm.nih.gov/pubmed/31712199
http://dx.doi.org/10.1128/AAC.01935-19