UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia

The possibility to use leptin therapeutically for lowering glucose levels in patients with type 1 diabetes has attracted interest. However, earlier animal models of type 1 diabetes are severely catabolic with very low endogenous leptin levels, unlike most patients with diabetes. Here, we aim to test...

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Detalles Bibliográficos
Autores principales: Zouhar, Petr, Rakipovski, Günaj, Bokhari, Muhammad Hamza, Busby, Oliver, Paulsson, Johan F., Conde-Frieboes, Kilian W., Fels, Johannes J., Raun, Kirsten, Andersen, Birgitte, Cannon, Barbara, Nedergaard, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985793/
https://www.ncbi.nlm.nih.gov/pubmed/31743040
http://dx.doi.org/10.1152/ajpendo.00253.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985793/
https://www.ncbi.nlm.nih.gov/pubmed/31743040
http://dx.doi.org/10.1152/ajpendo.00253.2019

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