Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer

Progressive fibrosis, functional liver failure, and cancer are the central liver-related outcomes of nonalcoholic steatohepatitis (NASH) but notoriously difficult to achieve in mouse models. We performed a direct, quantitative comparison of hepatic fibrosis progression in well-defined methionine- an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Guangyan, An, Ping, Vaid, Kahini A., Nasser, Imad, Huang, Pinzhu, Tan, Li, Zhao, Shuangshuang, Schuppan, Detlef, Popov, Yury V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985845/
https://www.ncbi.nlm.nih.gov/pubmed/31630534
http://dx.doi.org/10.1152/ajpgi.00041.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985845/
https://www.ncbi.nlm.nih.gov/pubmed/31630534
http://dx.doi.org/10.1152/ajpgi.00041.2019

Ejemplares similares