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Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer

Progressive fibrosis, functional liver failure, and cancer are the central liver-related outcomes of nonalcoholic steatohepatitis (NASH) but notoriously difficult to achieve in mouse models. We performed a direct, quantitative comparison of hepatic fibrosis progression in well-defined methionine- an...

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Detalles Bibliográficos
Autores principales:	Wei, Guangyan, An, Ping, Vaid, Kahini A., Nasser, Imad, Huang, Pinzhu, Tan, Li, Zhao, Shuangshuang, Schuppan, Detlef, Popov, Yury V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985845/ https://www.ncbi.nlm.nih.gov/pubmed/31630534 http://dx.doi.org/10.1152/ajpgi.00041.2019

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