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DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

AIM: Docosahexaenoic acid (DHA; C22; n-3) shows beneficial effects on Non-alcoholic fatty liver disease (NAFLD). Deacetylase Sirtuin1 (Sirt1) was reported to increase energy metabolism and decrease lipogenesis. Here, we investigated whether DHA plays a role in protecting against hepatic steatosis vi...

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Detalles Bibliográficos
Autores principales: Luo, Xiao, He, Zhangya, Sun, Xiaomin, Gu, Xinqian, Zhang, Wanyu, Gao, Jiayi, Li, Xiaomin, Jia, Ru, Wei, Junxiang, Yu, Yan, Luo, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985984/
https://www.ncbi.nlm.nih.gov/pubmed/32158242
http://dx.doi.org/10.2147/DMSO.S232279